How to Mix CBD Shots With Your Vape Juice Like a Pro

Make sure to use CBD Shots and not CBD oil!

8 May 2025 | Hannah Rubery

If you’re a fan of vaping and intrigued by the calming effects of CBD, combining the two might sound like a match made in heaven. The good news? You can mix CBD shots (or boosters) with your favourite vape juice for the ultimate custom experience.

With premixed CBD E-liquids already dominating the market, a lot of users wonder whether they can infuse traditional vape juices with CBD shots for more control over flavour and strength. Spoiler alert: you totally can! This guide will show you exactly how to do it safely and effectively while highlighting all the crucial dos and don’ts. If you've been searching for answers to "Can you add CBD to E-liquid?" or "How to mix CBD booster shot for the smoothest vape?", you're in the right place.

What Are CBD Shots?

Before jumping into the "how-to," let's break down what CBD shots are. Think of CBD shots (sometimes called boosters) as concentrated doses of CBD specifically formulated to be blended with E-liquids. Unlike traditional CBD oils, which are designed for ingestion or sublingual use, CBD shots contain a mix of CBD, vegetable glycerine (VG), and propylene glycol (PG)—making them effective for vaping.

Here’s what sets CBD shots apart:
• Designed for vaping: Unlike oils, they won’t harm your vape device.
• Customisable: You decide how much CBD goes into your E-liquid, tailoring your vape to your needs.
• Higher potency options: Many boosters offer a more concentrated CBD hit compared to premixed CBD vape juices.

Key takeaway: Always use CBD shots made only for vaping, do not use sublingually or ingest CBD shots. Never attempt to mix regular CBD oil with your vape juice. More on this below.

Safety First! Key Precautions When Mixing CBD and Vape Juice

Safety is paramount when working with CBD boosters and vape juice. Follow these precautions to ensure a seamless and enjoyable experience:

Stick to CBD Vape Shots Only
Using conventional CBD oil in a vape is a big no-no. These oils are typically mixed with carrier oils like MCT oil, which aren’t safe to inhale and may damage your lungs or vaping hardware.

Avoid Mixing CBD With Nicotine
Nicotine and CBD don’t play well together. Combining them can compromise the effects of CBD while increasing throat irritation. Stick to nicotine-free vape juices for the best results.

Use the Right Equipment
Make sure your vape device is compatible with CBD E-liquids and can handle varying VG/PG ratios. CBD shots typically work best with refillable pod systems or tanks offering low-moderate wattage.

Getting the Dosage Just Right

One of the biggest questions people ask when mixing CBD and vape juice is, "How much CBD should I use?" Overdoing it can make your experience less enjoyable (nobody wants to waste high-quality CBD!), so getting the balance right is key. Here’s a simple guide to help calculate your perfect dose of CBD for a 2ml tank:

Basic CBD Dosage Formula for E-liquids
• A 10ml bottle of CBD at 500mg concentration contains 50mg CBD per 1ml.
• A 10ml bottle of CBD at 300mg strength contains 30mg CBD per 1ml.
• For a 10mg per day dosage with a 500mg bottle, use 0.2ml (4 drops) per tank.
• For a 10mg per day dosage with a 300mg bottle, use 0.33ml (approx. 6 drops) per tank. To adjust your dosage:
1. Decide how much CBD you want based on your preferences (start low, e.g., 5–10mg, and work up).
2. Calculate the required CBD amount using the concentration of your booster.
3. Use a dropper for accurate measurements (1 drop = 0.05ml).

Quick Dosage Reference

Mixing Methods for CBD and Vape Juice

There are two easy ways to mix CBD shots with your E-liquid. Choose the method that works best for you based on your setup.

Method 1: Shot for a Shortfill
This approach is ideal for vapers who prefer larger batches of CBD-enhanced E-liquids.
1. Choose your Shortfill: Grab a regular shortfill bottle (e.g., 50ml) of nicotine-free E-liquid.
2. Add the CBD Booster: Pour the entire booster bottle into the shortfall.
3. Calculate Final Strength: Divide the booster CBD strength by the total E-liquid volume. For example:
• Adding a 300mg CBD booster into 60ml shortfill = 5mg CBD per ml.
4. Mix Well: Shake the bottle thoroughly to ensure an even distribution.
This method is ideal for users looking to create consistent, ready-to-use CBD vape juice.

Method 2: Add to the Tank
If you prefer more flexibility with your dosage, adding CBD shots directly to your vape tank is a great alternative.
1. Fill Your Tank: Choose your favourite vape juice and partially fill the tank.
2. Add CBD: Use a dropper to add the desired amount of CBD drops (e.g., 4–6 drops for 10mg).
3. Mix It Up: Swirl the tank gently or slightly tilt your device for even mixing.
4. Start Vaping: Enjoy your customised blend of CBD goodness.

This method is perfect for experimenting with dosages or changing flavours on the go.

The Benefits of Vaping CBD

While regulations limit specific health claims, many vapers choose to integrate CBD into their routines for its reported calming effects and personal benefits. Some reasons to consider vaping CBD include:
• Customised Experience: You control the flavour and strength.
• Fast Absorption: Vaping is one of the most effective ways to quickly feel the effects of CBD.
• Convenience: Mix up a batch or dose directly in your tank whenever you like.

Best of all? By creating your own blend, you can enjoy the cost efficiency of CBD boosters without sacrificing the flavours you love.

Master the Mix With Confidence

Mixing CBD shots with your vape juice doesn’t have to be complicated. With the right shots, calculations, and methods, you can completely tailor your vaping experience while enjoying the benefits CBD has to offer.

Whether you’re after smooth berry-flavoured puffs or earthy tones with a calming boost, try out these tips to create your ideal CBD-infused vape juice.